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Volume 141, Issue 1, Pages 198-200 (January 2006)


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Ocular Argyrosis After Long-Term Self-Application of Eyelash Tint

Mark J. Gallardo, MDa, J. Bradley Randleman, MDbCorresponding Author Informationemail address, Kristina M. Price, MDb, Daniel A. Johnson, MDa, Sharon Acosta, MDac, Hans E. Grossniklaus, MDb, R. Doyle Stulting, MD, PhDb

Accepted 22 July 2005. published online 31 October 2005.

Purpose

To report cases of ocular argyrosis that developed after long-term self-application of commercially available eyelash tint.

Design

Observational case series.

Methods

Case review, clinicopathologic analysis, and literature review.

Results

Three patients developed ocular argyrosis after the long-term self-application of Revlon Professional Roux Lash and Brow Tint (Colomer USA Corp, New York, New York, USA). Clinical evaluation revealed various degrees of silver deposition on the upper eyelid, lid margin, caruncle and conjunctiva, and diffuse Descemet’s membrane deposits. In one case, histologic examination demonstrated silver deposition in the basement membrane and superficial substantia propria of the conjunctiva.

Conclusions

Argyrosis can occur after long-term application of readily available eyelash tints, and the deposition of silver may be permanent. In certain circumstances, conjunctival argyrosis may simulate benign and malignant lesions, including conjunctival melanoma. These products should only be applied by trained cosmetologists.

a Department of Ophthalmology, University of Texas Health Sciences Center, San Antonio, Texas

b Emory University Department of Ophthalmology, Atlanta, Georgia

c Eye Associates of Seguin, Seguin, Texas

Corresponding Author InformationInquiries to J. Bradley Randleman, MD, 1365 B Clifton Road NE, Suite 4500, Atlanta, GA 30322

 Supported in part by Research to Prevent Blindness, Inc New York, New York, and the National Institutes of Health Core Grant P30 EYO6360, Bethesda, Maryland.

PII: S0002-9394(05)00856-1

doi:10.1016/j.ajo.2005.07.054


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