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Volume 141, Issue 1, Pages 71-78.e1 (January 2006)


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Outcomes in Patients Having Vitreous Presentation During Cataract Surgery Who Lack Capsular Support for a Nonsutured PC IOL

VA Cooperative Cataract Study GroupJoseph F. Collins, ScDabCorresponding Author Informationemail address, Ronald N. Gaster, MD (FACS)cd1, William F. Krol, PhDab

Accepted 18 August 2005. published online 10 October 2005.

Purpose

The study’s purpose was to determine the effect that lack of capsular support for a nonsutured posterior chamber (PC) intraocular lens IOL has on 1-year postoperative vision in patients suffering vitreous presentation (VP) during extracapsular cataract surgery.

Design

The study was a prospective, long-term clinical trial.

Methods

The study was conducted at 19 Department of Veterans Affairs medical centers. Patients having VP during cataract surgery with sufficient capsular support for a nonsutured PC IOL were randomized to receive either a PC IOL (230 patients) or an anterior chamber (AC) IOL (208 patients). Patients having insufficient capsular support (ICS) for a nonsutured PC IOL (143 patients) were prospectively followed in the same fashion. Best-corrected visual acuity (BCVA) at 1 year was obtained by a masked, certified examiner.

Results

The ICS group had considerably fewer patients with BCVA of 20/40 or better at 1 year (P < .0001) than the randomized PC IOL group (66.7% vs 91.1%) with a trend (P = .04) for having fewer patients than the randomized AC IOL group (66.7% vs 79.0%). The ICS group had significantly poorer rating of vision at 1 year by study raters, and the patients themselves than either of the randomized VP groups.

Conclusions

The lack of capsular support for the placement of a nonsutured PC IOL after VP during extracapsular cataract surgery or the severity of the complication of VP associated with lack of capsular support would appear to cause visual problems beyond that related to the type of intraocular lens implanted.

a VA Cooperative Studies Program Coordinating Center, Perry Point, Maryland

b University of Maryland School of Medicine, Baltimore, Maryland

c Department of Ophthalmology VA Medical Center Long Beach, Long Beach, California

d University of California, Irvine, California

Corresponding Author InformationInquiries to Joseph F. Collins, ScD, Director, CSPCC (151E), P.O. Box 1010, VA Medical Center, Perry Point, MD 21902; fax: (410) 642-1860

 Supported by the Cooperative Studies Program of the Department of Veterans Affairs Office of Research and Development.

1 Dr Gaster has equity ownership/stock options of over $10,000 in Pharmacia.

PII: S0002-9394(05)00965-7

doi:10.1016/j.ajo.2005.08.042


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