Surgical repair of full-thickness idiopathic macular holes associated with significant macular drusen
Presented in part at the annual meeting of the American Academy of Ophthalmology, Orlando, Florida, October 1999.
Received 25 October 1999; accepted 17 July 2000.
Abstract
Objective
To evaluate the visual and anatomic results of surgically repaired macular holes in eyes with intermediate or large-sized macular drusen.
Design
Retrospective noncomparative case series.
Participants
Thirty-four eyes of 32 patients undergoing macular hole surgery with preoperative intermediate or large-sized macular drusen as defined by the Age-Related Eye Disease Study (AREDS).
Intervention
Pars plana vitrectomy for standard macular hole repair performed by multiple surgeons.
Main outcome measures
Visual acuity, anatomic hole closure.
Results
Initial hole closure failed in 8 eyes (24%) overall, 5 of 28 eyes (18%) with AREDS category 2 drusen and 3 of 6 eyes (50%) with category 3 drusen (P = 0.1263). Final macular hole closure was seen in 93% of category 2 and 67% of category 3 eyes (P = 0.1347). Mean final visual acuity was 20/60 overall, 20/60 for category 2, and 20/50 for category 3 eyes.
Conclusions
A trend of reduced initial macular hole closure was seen in eyes with significant macular drusen. Reoperation improved closure rates. If closure was accomplished, visual outcomes were excellent.
Manuscript no. 99444.
aAssociated Retinal Consultants, PC, Department of Ophthalmology, Beaumont Eye Institute, Royal Oak, Michigan, USA
ABSTRACT