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Volume 108, Issue 10, Pages 1917-1921 (October 2001)


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Nyctalopia in antiquity: a review of the ancient Greek, Latin, and Byzantine literature

Dimitrios Brouzas, MDaCorresponding Author Informationemail address, Antonios Charakidas, MDa, Michael Vasilakis, MDa, Panagiotis Nikakis, MDa, Dimitrios Chatzoulis, MDa

Received 29 June 2000; accepted 13 June 2001.

Abstract 

Objective

To investigate the original definition and use of the term nyctalopia in ancient medical literature in view of the controversy between the English and some continental European literatures.

Design

Historical manuscript.

Methods

We review the use of the term in ancient Greek, Roman, and early Byzantine medical literature (5th century BC-7th century AD) and include a quick reference to the theories on its etymology.

Results

Physicians of antiquity defined as nyctalopia the symptom of defective dark adaptation, most commonly in the clinical setting of vitamin A deficiency. An alternative definition, the improvement of vision at night, is not recorded before the 2nd century AD and seems to result from a broader interpretation of the word, lacking medical acceptance at that time.

Conclusions

We propose to the ophthalmic community the use of the term nyctalopia exclusively for the description of defective dark adaptation.

Manuscript no. 200388.

a “Hippocration” General Hospital of Athens, Athens, Greece

Corresponding Author InformationCorrespondence to Dimitrios Brouzas, MD, 10 G. Papandreou Str, Byron-Athens GR-162 31, Greece

PII: S0161-6420(01)00802-8


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