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Volume 110, Issue 7, Pages 1403-1407 (July 2003)


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Periocular keratoacanthoma: Clinical features, pathology, and management

Presented in part as a poster at the Royal Australian and New Zealand College of Ophthalmology 33rd Annual Scientific Congress, Adelaide, Australia, October 2001.

Mark J Donaldson, MBBS1, Timothy J Sullivan, FRANZCO, FRACS1Corresponding Author Informationemail address, Kevin J Whitehead, FRCPA2, Richard M Williamson, FRCPA3

Received 14 January 2002; accepted 13 September 2002.

Abstract 

Purpose

To review the clinical features and results of surgical treatment of keratoacanthoma of the eyelids.

Design

Retrospective, interventional case series.

Participants

Ten patients.

Methods

Chart review of all eyelid keratoacanthomas treated between 1992 and 2001.

Main outcome measures

Adequate excision, recurrence rate, and complications.

Results

Patient ages ranged from 27 to 78 years, with a mean age of 59 years. Six patients were male and four were female. The lesion was found on the lower lid in five patients, upper lid in two, medial canthus in two, and lateral canthus in one. The maximum diameter of the lesion varied from 2 to 25 mm, with a mean of 7.2 mm. All lesions were treated by surgical excision, with frozen-section control of margins in five cases. All lesions were excised completely with clear resection margins, and there were no cases of recurrence. The only complication was a minor wound infection in one patient. Mean follow-up was 34.5 months.

Conclusions

Because of the aggressive nature and uncertain relationship to squamous cell carcinoma, we recommend excision of periocular keratoacanthoma. Surgical excision of eyelid keratoacanthoma provides good results and a very low risk of recurrence. Frozen-section control of margins should be used in selected cases to ensure complete excision.

1 Eyelid, Lacrimal and Orbital Clinic, Department of Ophthalmology, Royal Brisbane Hospital, Brisbane, Australia

2 Sullivan Nicolaides Pathology, Taringa, Queensland, Australia

3 Department of Pathology, Royal Brisbane Hospital, Brisbane, Australia

Corresponding Author InformationCorrespondence to Timothy J. Sullivan, FRANZCO, FRACS, Eyelid, Lacrimal and Orbital Clinic, Department of Ophthalmology, Royal Brisbane Hospital Herston, Queensland 4029, Australia.

 Manuscript no. 220037

PII: S0161-6420(03)00402-0

doi:10.1016/S0161-6420(03)00402-0


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