Poststreptococcal Syndrome Uveitis: A Descriptive Case Series and Literature Review
Presented as a scientific poster at: American Academy of Ophthalmology annual meeting, October, 2004; New Orleans, Louisiana.
Received 24 January 2005; accepted 22 December 2005.
Purpose
To describe the clinical features in a series of patients with poststreptococcal uveitis and to review literature on the pathophysiology and management.
Design
Retrospective and descriptive case series.
Participants
Ten consecutive cases of poststreptococcal syndrome uveitis diagnosed between 1996 and 2003.
Methods
Review of patient case notes.
Main Outcome Measures
Age, laterality, clinical features, and anti-streptococcal lysin O titers.
Results
Ten consecutive cases of poststreptococcal syndrome uveitis were identified. All our cases had bilateral nongranulomatous inflammation and raised anti-streptococcal lysin O titers. Collating data from previous reports and this series showed that 96% of the patients were below 40 years of age, and 87.5% had evidence of previous streptococcal infection. One third of the patients had posterior segment involvement. In our patients, this was in the form of vitritis, focal retinitis, optic disc swelling, and multifocal choroiditis.
Conclusions
Poststreptococcal syndrome uveitis should be considered in the etiology of acute bilateral nongranulomatous uveitis in children and young patients.
1Calderdale Royal Hospital, Halifax, United Kingdom
3Department of Ophthalmology, Bradford Royal Infirmary, Bradford, United Kingdom
Correspondence to Ms Seema Anand, 2, Woodlea Gate, Meanwood, Leeds, LS6 4SR, United Kingdom
Manuscript no. 2005-76.
No author has any financial interests in any of the products/equipment mentioned in the article. No author has any conflict of interest related to any product/equipment mentioned in the article or in the preparation and publication of the manuscript itself.
ABSTRACT