Estimating Choroidal Melanoma Volume: Comparison of Methods
Received 12 July 2006; accepted 23 August 2006. published online 23 February 2007.
Purpose
To evaluate published methods of estimating choroidal melanoma volume.
Design
Prospective consecutive case series.
Participants
Ten consecutive patients with primary choroidal melanoma.
Methods
After determination of tumor dimensions (largest tumor basal diameter, basal perpendicular diameter, and height), tumor volume was calculated for each tumor by using the 5 published methods. Percent differences in tumor volume were determined for each tumor as calculated by different methods.
Main Outcome Measure
Choroidal melanoma volume.
Results
The mean variation in estimated tumor volume expressed as a ratio was 2.33 (range, 1.64–3.84).
Conclusions
Choroidal melanoma volume calculation methods are inconsistent and caution is needed when volume measures are used for prognostic classification.
Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio.
Correspondence to Arun D. Singh, MD, Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195.
Manuscript no. 2006-768.
The authors have no conflicts of interest related to the article.
ABSTRACT