Prevalence of Myopia and Hyperopia in 6- to 72-Month-Old African American and Hispanic Children: The Multi-Ethnic Pediatric Eye Disease Study
Data from this study presented at: the Association for Research in Vision and Ophthalmology annual meeting, April 27 to May 1, 2008, Fort Lauderdale, Florida.
Received 28 January 2009; received in revised form 2 June 2009; accepted 8 June 2009. published online 18 November 2009.
Purpose
To determine the age-, gender-, and ethnicity-specific prevalence of myopia and hyperopia in African American and Hispanic children aged 6 to 72 months.
Design
Population-based cross-sectional study.
Participants
The Multi-Ethnic Pediatric Eye Disease Study is a population-based evaluation of the prevalence of vision disorders in children aged 6 to 72 months in Los Angeles County, California. Seventy-seven percent of eligible children completed a comprehensive eye examination. This report focuses on results from 2994 African American and 3030 Hispanic children.
Methods
Eligible children in 44 census tracts were identified during an in-home interview and scheduled for a comprehensive eye examination and in-clinic interview. Cycloplegic autorefraction was used to determine refractive error.
Main Outcome Measures
The proportion of children with spherical equivalent (SE) myopia ≤ −1.00 diopter (D) and SE hyperopia ≥ +2.00 D in the worse eye. Prevalence of myopia and hyperopia is also reported using alternative threshold definitions.
Results
Prevalence of myopia was higher in African American (6.6%) compared with Hispanic children (3.7%; P<0.001). Hispanics showed a higher prevalence of hyperopia than African American children (26.9% vs. 20.8% respectively, P<0.001). The prevalence of myopia showed a significant decreasing trend with age (P<0.001). Hyperopia prevalence reached a low point at approximately 24 months of age but increased and remained higher than that thereafter. No significant gender differences were found in the prevalence of refractive error for either ethnic group.
Conclusions
We observed ethnicity-related differences in both hyperopia and myopia prevalence in preschool children. The age-related decrease in myopia prevalence in preschool children could reflect early emmetropization and contrasts with the increase in myopia prevalence known to occur in older school-aged children. The limits of emmetropization are evident, however, in the persistently elevated prevalence of hyperopia beyond 24 months of age.
Financial Disclosure(s)
The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Available online: November 18, 2009.
Manuscript no. 2009-123.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Supported by the National Eye Institute, Bethesda, Maryland (grants EY14472 and EY03040), and an unrestricted grant from Research to Prevent Blindness, New York, New York. Dr Varma is a Research to Prevent Blindness Sybil B. Harrington Scholar.
The sponsor or funding organization had no role in the design or conduct of this research.
Correspondence: Rohit Varma, MD, MPH, Doheny Eye Institute, Department of Ophthalmology, 1450 San Pablo St., Room 4900, Los Angeles, CA 90033. E-mail: rvarma@usc.edu.
ABSTRACT