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Ophthalmology
Volume 117, Issue 8
, Pages 1567-1570
, August 2010
Three Major Loci Involved in Age-Related Macular Degeneration Are Also Associated with Polypoidal Choroidal Vasculopathy
References
- Indocyanine green videoangiography of idiopathic polypoidal choroidal vasculopathy. Retina. 1995;15:100–110
- . Idiopathic polypoidal choroidal vasculopathy (IPCV). Retina. 1990;10:1–8
- Polypoidal choroidal vasculopathy treated with macular translocation: clinical pathological correlation. Br J Ophthalmol. 2002;86:321–327
- . The origins of polypoidal choroidal vasculopathy. Br J Ophthalmol. 2005;89:602–607
- Morphologic and angiographic assessment of the macula after macular translocation surgery with 360 degrees retinotomy. Ophthalmology. 2003;110:2403–2408
- Polypoidal choroidal vasculopathy and neovascularized age-related macular degeneration. Arch Ophthalmol. 1999;117:1503–1510
- One-year outcomes of photodynamic therapy in age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese patients. Ophthalmology. 2008;115:141–146
- Idiopathic polypoidal choroidal vasculopathy of the macula. Ophthalmology. 1998;105:1380–1385
- The expanding clinical spectrum of idiopathic polypoidal choroidal vasculopathy. Arch Ophthalmol. 1997;115:478–485
- Treatment of polypoidal choroidal vasculopathy with photodynamic therapy. Retina. 2002;22:529–535
- Photodynamic therapy with verteporfin for polypoidal choroidal vasculopathy of the macula. Ophthalmologica. 2004;218:193–201
- Photodynamic therapy with verteporfin for symptomatic polypoidal choroidal vasculopathy: one-year results of a prospective case series. Ophthalmology. 2004;111:1576–1584
- . Genetic susceptibility to age-related macular degeneration: a paradigm for dissecting complex disease traits. Hum Mol Genet. 2007;16:R174–R182
- . A clinician's view of the molecular genetics of age-related maculopathy. Arch Ophthalmol. 2007;125:21–29
- A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A. 2005;102:7227–7232
- Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Gen. 2006;38:458–462
- Complement factor H polymorphism and age-related macular degeneration. Science. 2005;308:421–424
- Complement factor H variant increases the risk of age-related macular degeneration. Science. 2005;308:419–421
- Susceptibility genes for age-related maculopathy on chromosome 10q26. Am J Hum Genet. 2005;77:389–407
- Complement factor H polymorphism in age-related macular degeneration. Science. 2005;308:385–389
- Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet. 2005;14:3227–3236
- LOC387715/HTRA1 variants in polypoidal choroidal vasculopathy and age-related macular degeneration in a Japanese population. Am J Ophthalmol. 2007;144:608–612
- Association of LOC387715 A69S with vitreous hemorrhage in polypoidal choroidal vasculopathy. Am J Ophthalmol. 2008;145:1058–1062
- ARMS2 (LOC387715) variants in Japanese patients with exudative age-related macular degeneration and polypoidal choroidal vasculopathy. Am J Ophthalmol. 2009;147:1037–1041
- Association analysis of CFH, C2, BF, and HTRA1 gene polymorphisms in Chinese patients with polypoidal choroidal vasculopathy. Invest Ophthalmol Vis Sci. 2008;49:2613–2619
- . Coding variant I62V in the complement factor H gene is strongly associated with polypoidal choroidal vasculopathy. Ophthalmology. 2009;116:304–310
- Incidence and clinical patterns of polypoidal choroidal vasculopathy in Korean patients. Jpn J Ophthalmol. 2008;52:57–62
- Clinical characteristics of exudative age-related macular degeneration in Japanese patients. Am J Ophthalmol. 2007;144:15–22
- Polypoidal choroidal vasculopathy: incidence, demographic features, and clinical characteristics. Arch Ophthalmol. 2003;121:1392–1396
- HRTA1 promoter polymorphism predisposes Japanese to age-related macular degeneration. Mol Vis [serial online]. 2007;13:545–548http://www.molvis.org/molvis/v13/a58/Accessed November 27, 2009
- Elevated C-reactive protein levels in patients with polypoidal choroidal vasculopathy and patients with neovascular age-related macular degeneration. Ophthalmology. 2007;114:1722–1727
- Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes that protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications. Ann Med. 2006;38:592–604
Manuscript no. 2009-1288.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Supported by grants National Institutes of Health EY13435, EY017404, The Macula Foundation, Inc., and an unrestricted grant to the Department of Ophthalmology, Columbia University, from Research to Prevent Blindness, Inc. Dr. Imamura was funded by grants from Koureisha Ganshikkan Kenkyu Zaidan, Mishima Saiichi-kinen Gankakenkyu Kokusaikouryu Kikin, and Takeda Kagaku Shinkou Zaidan.
PII: S0161-6420(09)01443-2
doi: 10.1016/j.ophtha.2009.12.018
© 2010 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.
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Ophthalmology
Volume 117, Issue 8
, Pages 1567-1570
, August 2010

