Ophthalmology
Volume 117, Issue 9 , Pages 1705-1712 , September 2010

Incidence of Glaucomatous Visual Field Loss: A Ten-Year Follow-up from the Rotterdam Study

Presented at: the Association for Research in Vision and Ophthalmology 2009 Annual Meeting, May 2009, Fort Lauderdale, Florida.

  • Monika A. Czudowska, MD

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Wishal D. Ramdas, MD

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Roger C.W. Wolfs, MD, PhD

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Albert Hofman, MD, PhD

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Paulus T.V.M. De Jong, MD, PhD

      Affiliations

    • Ophthalmogenetics, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands
    • Ophthalmology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands
    • ,
  • Johannes R. Vingerling, MD, PhD

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Corresponding Author InformationCorrespondence: Johannes R. Vingerling, MD, PhD, Departments of Ophthalmology and Epidemiology, Erasmus Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    • ,
  • Nomdo M. Jansonius, MD, PhD

      Affiliations

    • Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Ophthalmology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Received 27 May 2009 ,Revised 15 January 2010 ,Accepted 19 January 2010.

References 

  1. Anton A, Andrada MT, Mujica V, et al. Prevalence of primary open-angle glaucoma in a Spanish population: the Segovia study. J Glaucoma. 2004;13:371–376
  2. Bengtsson B. The prevalence of glaucoma. Br J Ophthalmol. 1981;65:46–49
  3. Bonomi L, Marchini G, Marraffa M, et al. Prevalence of glaucoma and intraocular pressure distribution in a defined population: the Egna-Neumarkt Study. Ophthalmology. 1998;105:209–215
  4. Cedrone C, Culasso F, Cesareo M, et al. Prevalence of glaucoma in Ponza, Italy: a comparison with other studies. Ophthalmic Epidemiol. 1997;4:59–72
  5. Kahn HA, Leibowitz HM, Ganley JP, et al. The Framingham Eye Study (I. Outline and major prevalence findings). Am J Epidemiol. 1977;106:17–32
  6. Klein BE, Klein R, Sponsel WE, et al. Prevalence of glaucoma: the Beaver Dam Eye Study. Ophthalmology. 1992;99:1499–1504
  7. Leske MC, Connell AM, Schachat AP, Hyman L Barbados Eye Study Group. The Barbados Eye Study: prevalence of open angle glaucoma. Arch Ophthalmol. 1994;112:821–829
  8. Mitchell P, Smith W, Attebo K, Healey PR. Prevalence of open-angle glaucoma in Australia: the Blue Mountains Eye Study. Ophthalmology. 1996;103:1661–1669
  9. Tielsch JM, Sommer A, Katz J, et al. Racial variations in the prevalence of primary open-angle glaucoma: the Baltimore Eye Survey. JAMA. 1991;266:369–374
  10. Wensor MD, McCarty CA, Stanislavsky YL, et al. The prevalence of glaucoma in the Melbourne Visual Impairment Project. Ophthalmology. 1998;105:733–739
  11. Wolfs RC, Borger PH, Ramrattan RS, et al. Changing views on open-angle glaucoma: definitions and prevalences—the Rotterdam Study. Invest Ophthalmol Vis Sci. 2000;41:3309–3321
  12. Bengtsson BO. Incidence of manifest glaucoma. Br J Ophthalmol. 1989;73:483–487
  13. de Voogd S, Ikram MK, Wolfs RC, et al. Incidence of open-angle glaucoma in a general elderly population: the Rotterdam Study. Ophthalmology. 2005;112:1487–1493
  14. Ekstrom C. Elevated intraocular pressure and pseudoexfoliation of the lens capsule as risk factors for chronic open-angle glaucoma: a population-based five-year follow-up study. Acta Ophthalmol (Copenh). 1993;71:189–195
  15. Leske MC, Connell AM, Wu SY, et al. Barbados Eye Studies Group Incidence of open-angle glaucoma: the Barbados Eye Studies. Arch Ophthalmol. 2001;119:89–95
  16. Leske MC, Wu SY, Honkanen R, et al. Barbados Eye Studies Group Nine-year incidence of open-angle glaucoma in the Barbados Eye Studies. Ophthalmology. 2007;114:1058–1064
  17. Mukesh BN, McCarty CA, Rait JL, Taylor HR. Five-year incidence of open-angle glaucoma: the Visual Impairment Project. Ophthalmology. 2002;109:1047–1051
  18. de Jong PT, Jansonius NM, Wolfs RC, Zegers RH. Epidemiology of and risk factors for primary open-angle glaucoma. In:  Tombran-Tink J,  Barnstable CJ,  Shields MB editor. Mechanisms of the Glaucomas: Disease Processes and Therapeutic Modalities. Totowa, NJ: Humana Press; 2008;p. 19–33
  19. Burr JM, Mowatt G, Hernandez R, et al. The clinical effectiveness and cost-effectiveness of screening for open angle glaucoma: a systematic review and economic evaluation. Health Technol Assess. 2007;11:iii–iv, ix–x, 1–190
  20. Stoutenbeek R, de Voogd S, Wolfs RC, et al. The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening. Br J Ophthalmol. 2008;92:1222–1226
  21. Vaahtoranta-Lehtonen H, Tuulonen A, Aronen P, et al. Cost effectiveness and cost utility of an organized screening programme for glaucoma. Acta Ophthalmol Scand. 2007;85:508–518
  22. Hofman A, Breteler MM, van Duijn CM, et al. The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol. 2009;24:553–572
  23. Asman P, Heijl A. Evaluation of methods for automated hemifield analysis in perimetry. Arch Ophthalmol. 1992;110:820–826
  24. Skenduli-Bala E, de Voogd S, Wolfs RC, et al. Causes of incident visual field loss in a general elderly population: the Rotterdam study. Arch Ophthalmol. 2005;123:233–238
  25. Katz J, Sommer A, Gaasterland DE, Anderson DR. Comparison of analytic algorithms for detecting glaucomatous visual field loss. Arch Ophthalmol. 1991;109:1684–1689
  26. Rothman KJ, Greenland S. Measures of disease frequency. In:  Rothman KJ,  Greenland S editor. Modern Epidemiology. 2nd ed.. Philadelphia, PA: Lippincott-Raven; 1998;p. 39–40
  27. Bozkurt B, Yilmaz PT, Irkec M. Relationship between Humphrey 30-2 SITA Standard Test, Matrix 30-2 threshold test, and Heidelberg Retina Tomograph in ocular hypertensive and glaucoma patients. J Glaucoma. 2008;17:203–210
  28. Cello KE, Nelson-Quigg JM, Johnson CA. Frequency doubling technology perimetry for detection of glaucomatous visual field loss. Am J Ophthalmol. 2000;129:314–322
  29. Heeg GP, Blanksma LJ, Hardus PL, Jansonius NM. The Groningen Longitudinal Glaucoma Study (I. Baseline sensitivity and specificity of the frequency doubling perimeter and the GDx nerve fibre analyser). Acta Ophthalmol Scand. 2005;83:46–52
  30. Heeg GP, Jansonius NM. The Groningen Longitudinal Glaucoma Study (III. The predictive value of frequency-doubling perimetry and GDx nerve fibre analyser test results for the development of glaucomatous visual field loss). Eye. 2009;23:1647–1652
  31. Trible JR, Schultz RO, Robinson JC, Rothe TL. Accuracy of glaucoma detection with frequency-doubling perimetry. Am J Ophthalmol. 2000;129:740–745
  32. Schoff EO, Hattenhauer MG, Ing HH, et al. Estimated incidence of open-angle glaucoma in Olmsted County, Minnesota. Ophthalmology. 2001;108:882–886
  33. Mitchell P, Hourihan F, Sandbach J, Wang JJ. The relationship between glaucoma and myopia: the Blue Mountains Eye Study. Ophthalmology. 1999;106:2010–2015
  34. Wu SY, Nemesure B, Leske MC Barbados Eye Studies Group. Refractive errors in a black adult population: the Barbados Eye Study. Invest Ophthalmol Vis Sci. 1999;40:2179–2184
  35. Grodum K, Heijl A, Bengtsson B. Refractive error and glaucoma. Acta Ophthalmol Scand. 2001;79:560–566
  36. Wong TY, Klein BE, Klein R, et al. Refractive errors, intraocular pressure, and glaucoma in a white population. Ophthalmology. 2003;110:211–217
  37. Le A, Mukesh BN, McCarty CA, Taylor HR. Risk factors associated with the incidence of open-angle glaucoma: the Visual Impairment Project. Invest Ophthalmol Vis Sci. 2003;44:3783–3789
  38. Leske MC, Wu SY, Hennis A, et al. BESs Study Group Risk factors for incident open-angle glaucoma: the Barbados Eye Studies. Ophthalmology. 2008;115:85–93
  39. Leske MC, Connell AM, Wu SY, et al. Barbados Eye Studies Group Risk factors for open-angle glaucoma: the Barbados Eye Study. Arch Ophthalmol. 1995;113:918–924
  40. Mitchell P, Rochtchina E, Lee AJ, Wang JJ. Bias in self-reported family history and relationship to glaucoma: the Blue Mountains Eye Study. Ophthalmic Epidemiol. 2002;9:333–345
  41. Suzuki Y, Iwase A, Araie M, et al. Tajimi Study Group Risk factors for open-angle glaucoma in a Japanese population: the Tajimi Study. Ophthalmology. 2006;113:1613–1617
  42. Tielsch JM, Katz J, Sommer A, et al. Family history and risk of primary open angle glaucoma: the Baltimore Eye Survey. Arch Ophthalmol. 1994;112:69–73
  43. Borger PH, van Leeuwen R, Hulsman CA, et al. Is there a direct association between age-related eye diseases and mortality? (The Rotterdam Study). Ophthalmology. 2003;110:1292–1296
  44. Akbari M, Akbari S, Pasquale LR. The association of primary open-angle glaucoma with mortality: a meta-analysis of observational studies. Arch Ophthalmol. 2009;127:204–210

 Manuscript no. 2009-720.

 Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.

 Financial support: The Netherlands Organization for Health Research and Development (ZonMw) grant 2200.0035, The Hague; Lijf en Leven, Krimpen a/d Lek; MD Fonds, Utrecht. Oogfonds Nederland, Utrecht; MD Fonds, Utrecht; Stichting Nederlands Oogheelkundig Onderzoek, Nijmegen/Rotterdam; Swart van Essen, Rotterdam; Netherlands Organisation for Scientific Research, The Hague; Bevordering van Volkskracht, Rotterdam; Blindenhulp, The Hague; Landelijke Stichting voor Blinden en Slechtzienden, Utrecht; Rotterdamse Vereniging voor Blindenbelangen, Rotterdam; OOG, The Hague; Algemene Nederlandse Vereniging ter Voorkoming van Blindheid, Doorn; Laméris Ootech BV, Nieuwegein; Medical Workshop BV, Groningen; Topcon Europe BV, Capelle aan de IJssel, all in the Netherlands, and Heidelberg Engineering, Dossenheim, Germany. The sponsors or funding organizations had no role in the design, conduct, analysis or publication of this research.

 This population-based prospective study estimates the 10-year incidence of glaucomatous visual field loss in a general elderly white population to be approximately 3%.

PII: S0161-6420(10)00063-1

doi: 10.1016/j.ophtha.2010.01.034

Ophthalmology
Volume 117, Issue 9 , Pages 1705-1712 , September 2010

Article Tools

* Image Usage & Resolution