Ophthalmology
Volume 118, Issue 1 , Pages 66-70 , January 2011

The Concave Iris in Pigment Dispersion Syndrome

  • Lance Liu, MBBS, FRANZCO

      Affiliations

    • Glaucoma Unit, Royal Victorian Eye and Ear Hospital, Victoria, Australia
    • Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    • Preston Eye Clinic, Preston, Victoria, Australia
    • Corresponding Author InformationCorrespondence: Lance Liu, MBBS, FRANZCO, Preston Eye Clinic, 268 Murray Road, Preston VIC 3072, Australia
    • ,
  • Ee Lin Ong

      Affiliations

    • Glaucoma Unit, Royal Victorian Eye and Ear Hospital, Victoria, Australia
    • Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    • ,
  • Jonathan Crowston, PhD, FRCOphth

      Affiliations

    • Glaucoma Unit, Royal Victorian Eye and Ear Hospital, Victoria, Australia
    • Preston Eye Clinic, Preston, Victoria, Australia

Received 9 November 2009 ,Revised 21 March 2010 ,Accepted 30 April 2010.

References 

  1. Ritch R, Liebmann JM. Role of ultrasound biomicroscopy in the differentiation of block glaucomas. Curr Opin Ophthalmol. 1998;9:39–45
  2. Gillies WE, Brooks AM. Clinical features at presentation of anterior segment pigment dispersion syndrome. Clin Experiment Ophthalmol. 2001;29:125–127
  3. Sowka J. Pigment dispersion syndrome and pigmentary glaucoma. Optometry. 2004;75:115–122
  4. Ritch R, Mudumbai R, Liebmann JM. Combined exfoliation and pigment dispersion: paradigm of an overlap syndrome. Ophthalmology. 2000;107:1004–1008
  5. Siddiqui Y, Ten Hulzen RD, Cameron JD, et al. What is the risk of developing pigmentary glaucoma from pigment dispersion syndrome?. Am J Ophthalmol. 2003;135:794–799
  6. Speakman JS. Pigmentary dispersion. Br J Ophthalmol. 1981;65:249–251
  7. Campbell DG. Pigmentary dispersion and glaucoma: a new theory. Arch Ophthalmol. 1979;97:1667–1672
  8. Gottanka J, Johnson DH, Grehn F, Lutjen-Drecoll E. Histologic findings in pigment dispersion syndrome and pigmentary glaucoma. J Glaucoma. 2006;15:142–151
  9. Karickhoff JR. Pigmentary dispersion syndrome and pigmentary glaucoma: a new mechanism concept, a new treatment, and a new technique. Ophthalmic Surg. 1992;23:269–277
  10. Potash SD, Tello C, Liebmann J, Ritch R. Ultrasound biomicroscopy in pigment dispersion syndrome. Ophthalmology. 1994;101:332–339
  11. Pavlin CJ, Macken P, Trope GE, et al. Accommodation and iridotomy in the pigment dispersion syndrome. Ophthalmic Surg Lasers. 1996;27:113–120
  12. Pavlin CJ, Harasiewicz K, Foster FS. Posterior iris bowing in pigmentary dispersion syndrome caused by accommodation. Am J Ophthalmol. 1994;118:114–116
  13. Pavlin CJ. Ultrasound biomicroscopy in pigment dispersion syndrome [letter]. Ophthalmology. 1994;101:1475–1477
  14. Adam RS, Pavlin CJ, Ulanski LJ. Ultrasound biomicroscopic analysis of iris profile changes with accommodation in pigmentary glaucoma and relationship to age. Am J Ophthalmol. 2004;138:652–654
  15. Dorairaj S, Oliveira C, Fose AK, et al. Accommodation-induced changes in iris curvature. Exp Eye Res. 2008;86:220–225
  16. Leung CK, Chan WM, Ko CY, et al. Visualization of anterior chamber angle dynamics using optical coherence tomography. Ophthalmology. 2005;112:980–984
  17. Kanadani FN, Dorairaj S, Langlieb AM, et al. Ultrasound biomicroscopy in asymmetric pigment dispersion syndrome and pigmentary glaucoma. Arch Ophthalmol. 2006;124:1573–1576
  18. Ritch R. A unification hypothesis of pigment dispersion syndrome. Trans Am Ophthalmol Soc. 1996;94:381–409
  19. Moroi SE, Lark KK, Sieving PA, et al. Long anterior zonules and pigment dispersion. Am J Ophthalmol. 2003;136:1176–1178
  20. Kupfer C, Kuwabara T, Kaiser-Kupfer M. The histopathology of pigmentary dispersion syndrome with glaucoma. Am J Ophthalmol. 1975;80:857–862
  21. Carassa RG, Bettin P, Fiori M, Brancato R. Nd:YAG laser iridotomy in pigment dispersion syndrome: an ultrasound biomicroscopic study. Br J Ophthalmol. 1998;82:150–153
  22. Laemmer R, Mardin CY, Juenemann AG. Visualization of changes of the iris configuration after peripheral laser iridotomy in primary melanin dispersion syndrome using optical coherence tomography. J Glaucoma. 2008;17:569–570
  23. Liebmann JM, Tello C, Chew SJ, et al. Prevention of blinking alters iris configuration in pigment dispersion syndrome and in normal eyes. Ophthalmology. 1995;102:446–455
  24. Pavlin CJ, Burns PN, Foster FS. Use of microbubble ultrasound contrast agent to demonstrate the iris valve effect in human eye bank eyes. Am J Ophthalmol. 1998;126:719–720
  25. Breingan PJ, Esaki K, Ishikawa H, et al. Iridolenticular contact decreases following laser iridotomy for pigment dispersion syndrome. Arch Ophthalmol. 1999;117:325–328
  26. Duncan G, Wormstone IM, Davies PD. The aging human lens: structure, growth, and physiological behaviour. Br J Ophthalmol. 1997;81:818–823
  27. Bovell AM, Damji KF, Dohadwala AA, et al. Familial occurrence of pigment dispersion syndrome. Can J Ophthalmol. 2001;36:11–17
  28. Lehto I, Vesti E. Diagnosis and management of pigmentary glaucoma. Curr Opin Ophthalmol. 1998;9:61–64
  29. Farrar SM, Shields MB, Miller KN, Stoup CM. Risk factors for the development and severity of glaucoma in the pigment dispersion syndrome. Am J Ophthalmol. 1989;108:223–229
  30. Richter CU, Richardson TM, Grant WM. Pigmentary dispersion syndrome and pigmentary glaucoma: a prospective study of the natural history. Arch Ophthalmol. 1986;104:211–215
  31. Gandolfi SA, Vecchi M. Effect of a YAG laser iridotomy on intraocular pressure in pigment dispersion syndrome. Ophthalmology. 1996;103:1693–1695

 Manuscript no. 2009-1562.

 Financial Disclosure(s): The author(s) have made the following disclosure(s): Dr Crowston is a consultant for the following: Pfizer, New York, New York; Alcon, Hünenberg, Switzerland; and Allergan, Irvine, CA; and Merck, Whitehouse Station, NJ.

PII: S0161-6420(10)00512-9

doi: 10.1016/j.ophtha.2010.04.039

Ophthalmology
Volume 118, Issue 1 , Pages 66-70 , January 2011

Article Tools

* Image Usage & Resolution